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1

ChemInform Abstract: Novel Esters and Amides of Nonsteroidal Antiinflammatory Carboxylic Acids as Antioxidants and Antiproliferative Agents.

Mark R. Hellberg, Abdelmoula Namil, Pete Delgado, Karen C. David, Timothy L. Kessler, Gustav Graff, Karen S. Haggard, Jon C. Nixon

Journal:

Year:

1999

File:

PDF, 31 KB

1999

2

15-Fluoro prostaglandin FP agonists: a new class of topical ocular hypotensives

Peter Klimko, Mark Hellberg, Marsha McLaughlin, Najam Sharif, Bryon Severns, Gary Williams, Karen Haggard, John Liao

Journal:

Bioorganic & Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 539 KB

english, 2004

3

Discovery of 13-oxa prostaglandin analogs as antiglaucoma agents: Synthesis and biological activity

Zixia Feng, Mark R. Hellberg, Najam A. Sharif, Marsha A. McLaughlin, Gary W. Williams, Daniel Scott, Tony Wallace

Journal:

Bioorganic & Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 334 KB

english, 2009

4

AL-12182, a novel 11-oxa prostaglandin analog with topical ocular hypotensive activity in the monkey

Robert D Selliah, Mark R Hellberg, Najam A Sharif, Marsha A McLaughlin, Gary W Williams, Daniel A Scott, David Earnest, Karen S Haggard, W Dennis Dean, Pete Delgado, Michael S Gaines, Raymond E Conrow

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 277 KB

english, 2004

5

Novel benzodifuran analogs as potent 5-HT2A receptor agonists with ocular hypotensive activity

Zixia Feng, Suchismita Mohapatra, Peter G. Klimko, Mark R. Hellberg, Jesse A. May, Curtis Kelly, Gary Williams, Marsha A. McLaughlin, Najam A. Sharif

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 158 KB

english, 2007

6

2,3-Diaminopyrazines as rho kinase inhibitors

Alan J. Henderson, Mark Hadden, Cheng Guo, Neema Douglas, Helene Decornez, Mark R. Hellberg, Andrew Rusinko, Marsha McLaughlin, Naj Sharif, Colene Drace, Raj Patil

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 983 KB

english, 2010

7

Water-soluble PDE4 inhibitors for the treatment of dry eye

Steven P. Govek, Guy Oshiro, John V. Anzola, Clay Beauregard, Jasmine Chen, Avery R. Coyle, Daniel A. Gamache, Mark R. Hellberg, Jennifer N. Hsien, Julia M. Lerch, John C. Liao, James W. Malecha, Lena

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 564 KB

english, 2010

8

Benzothiophene containing Rho kinase inhibitors: Efficacy in an animal model of glaucoma

Robert L. Davis, Mehmet Kahraman, Thomas J. Prins, Yan Beaver, Travis G. Cook, Jessica Cramp, Charmagne S. Cayanan, Elisabeth M.M. Gardiner, Marsha A. McLaughlin, Abbot F. Clark, Mark R. Hellberg, And

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 500 KB

english, 2010

9

Synthesis of novel prostaglandins containing a boronate in the α chain

Zixia Feng, Mark Hellberg

Journal:

Tetrahedron Letters

Year:

2000

Language:

english

File:

PDF, 132 KB

english, 2000

10

Density functional studies of single molecule magnets

Jens Kortus, Mark R. Pederson, Tunna Baruah, N. Bernstein, C.S. Hellberg

Journal:

Year:

2003

Language:

english

File:

PDF, 196 KB

english, 2003

11

A preliminary investigation of Mesoionic Xanthine analogues as inhibitors of platelet aggregation

Mark Hellberg, James F. Stubbins, Richard A. Glennon

Journal:

Bioorganic & Medicinal Chemistry

Year:

2000

Language:

english

File:

PDF, 165 KB

english, 2000

12

3-Oxa-15-cyclohexyl prostaglandin DP receptor agonists as topical antiglaucoma agents

Mark R. Hellberg, Raymond E. Conrow, Najam A. Sharif, Marsha A. McLaughlin, John E. Bishop, Julie Y. Crider, W.Dennis Dean, Kevin A. DeWolf, David R. Pierce, Verney L. Sallee, Robert D. Selliah, Bryon

Journal:

Bioorganic & Medicinal Chemistry

Year:

2002

Language:

english

File:

PDF, 317 KB

english, 2002

13

Investigation into A antigen expression on O2 heterozygous group O–labeled red blood cell units

Mark H. Yazer, Annika K. Hult, Åsa Hellberg, Bahram Hosseini-Maaf, Monica M. Palcic, Martin L. Olsson

Journal:

Transfusion (Wiley)

Year:

2008

Language:

english

File:

PDF, 308 KB

english, 2008

14

Weak A phenotypes associated with novel ABO alleles carrying the A2-related 1061C deletion and various missense substitutions

Annika K. Hult, Mark H. Yazer, René Jørgensen, Åsa Hellberg, Hein Hustinx, Thierry Peyrard, Monica M. Palcic, Martin L. Olsson

Journal:

Transfusion (Wiley)

Year:

2010

Language:

english

File:

PDF, 1.39 MB

english, 2010

15

Characterization of theIn VitroAnti-inflammatory Activity of AL-5898 and Related Benzopyranyl Esters and Amides

Karen C. David, Milton T. Brady, Lori K. Weimer, Mark R. Hellberg, Jon C. Nixon, Gustav Graff

Journal:

Year:

2003

Language:

english

File:

PDF, 229 KB

english, 2003

16

Identification and Characterization of the Ocular Hypotensive Efficacy of Travoprost, a Potent and Selective FP Prostaglandin Receptor Agonist, and AL-6598, a DP Prostaglandin Receptor Agonist

Mark R. Hellberg, Marsha A. McLaughlin, Naj A. Sharif, Louis DeSantis, Tom R. Dean, Evan P. Kyba, John E. Bishop, Peter G. Klimko, Paul W. Zinke, Robert D. Selliah, George Barnes, Joseph DeFaller, Ang

Journal:

Survey of Ophthalmology

Year:

2002

Language:

english

File:

PDF, 481 KB

english, 2002

17

β-Oxygenated Analogues of the 5-HT 2A Serotonin Receptor Agonist 1-(4-Bromo-2,5-dimethoxyphenyl)-2-aminopropane

Glennon, Richard A., Bondarev, Mikhail L., Khorana, Nantaka, Young, Richard, May, Jesse A., Hellberg, Mark R., McLaughlin, Marsha A., Sharif, Najam A.

Journal:

Journal of Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 137 KB

english, 2004

18

Preclinical Efficacy of Travoprost, a Potent and Selective FP Prostaglandin Receptor Agonist

Hellberg, Mark R., Sallee, Verney L., McLaughlin, Marsha A., Sharif, Naj A., Desantis, Louis, Dean, Tom R., Zinke, Paul W.

Journal:

Journal of Ocular Pharmacology and Therapeutics

Year:

2001

Language:

english

File:

PDF, 237 KB

english, 2001

19

The Hydrolysis of the Prostaglandin Analog Prodrug Bimatoprost to 17-Phenyl-trinor PGF 2 α by Human and Rabbit Ocular Tissue

Hellberg, Mark R., Ke, Tai-Lee, Haggard, Karen, Klimko, Peter G., Dean, Tom R., Graff, Gustav

Journal:

Journal of Ocular Pharmacology and Therapeutics

Year:

2003

Language:

english

File:

PDF, 124 KB

english, 2003

20

Identification and Characterization of a Small Molecule Inhibitor of Fatty Acid Binding Proteins

Hertzel, Ann V., Hellberg, Kristina, Reynolds, Joseph M., Kruse, Andrew C., Juhlmann, Brittany E., Smith, Anne J., Sanders, Mark A., Ohlendorf, Douglas H., Suttles, Jill, Bernlohr, David A.

Journal:

Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 893 KB

english, 2009

21

In vivo optimization of 2,3-diaminopyrazine Rho Kinase inhibitors for the treatment of glaucoma

Chen, Hwang-Hsing, Namil, Abdelmoulah, Severns, Bryon, Ward, Jennifer, Kelly, Curtis, Drace, Colene, McLaughlin, Marsha A., Yacoub, Shenouda, Li, Byron, Patil, Raj, Sharif, Naj, Hellberg, Mark R., Rus

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2014

Language:

english

File:

PDF, 1.19 MB

english, 2014

22

Novel Esters and Amides of Nonsteroidal Antiinflammatory Carboxylic Acids as Antioxidants and Antiproliferative Agents

Hellberg, Mark R., Namil, Abdelmoula, Delgado, Pete, David, Karen C., Kessler, Timothy L., Graff, Gustav, Haggard, Karen S., Nixon, Jon C.

Journal:

Journal of Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 200 KB

english, 1999

23

Novel Binding Mode of Hydroxamate Inhibitors to Human Carbonic Anhydrase II

Scolnick, Laura R., Clements, Adrienne M., Liao, John, Crenshaw, Lori, Hellberg, Mark, May, Jesse, Dean, Tom R., Christianson, David W.

Journal:

Journal of the American Chemical Society

Year:

1997

Language:

english

File:

PDF, 85 KB

english, 1997

24

Spin System from First-Principles Density-Functional Calculations

Kortus, Jens, Hellberg, C. Stephen, Pederson, Mark R.

Journal:

Physical Review Letters

Year:

2001

Language:

english

File:

PDF, 88 KB

english, 2001

25

Evaluation of AL-05712 and AL-05741 as Thioltransferase Mimics for the Prevention and Recovery of Pre-Cataractous Changes in Lens

DICKERSON, JAIME E., HELLBERG, MARK, LOU, MARJORIE F.

Journal:

Journal of Ocular Pharmacology and Therapeutics

Year:

1998

Language:

english

File:

PDF, 876 KB

english, 1998

26

acetate

Park, Kyungwha, Pederson, Mark R., Hellberg, C. Stephen

Journal:

Physical Review B

Year:

2004

Language:

english

File:

PDF, 70 KB

english, 2004

27

Investigating the breakup dynamics of dihydrogen sulfide ions recombining with electrons

Hellberg, Fredrik, Zhaunerchyk, Vitali, Ehlerding, Anneli, Geppert, Wolf D., Larsson, Mats, Thomas, Richard D., Bannister, Mark E., Bahati, Eric, Vane, C. Randy, Österdahl, Fabian, Hlavenka, Petr, af

Journal:

The Journal of Chemical Physics

Year:

2005

Language:

english

File:

PDF, 470 KB

english, 2005

28

Ocular Hypotensive Response in Nonhuman Primates of (8 R )-1-[(2 S )-2-Aminopropyl]-8,9-dihydro-7 H -pyrano[2,3- g ]indazol-8-ol a Selective 5-HT 2 Receptor Agonist

May, Jesse A., Sharif, Najam A., McLaughlin, Marsha A., Chen, Hwang-Hsing, Severns, Bryon S., Kelly, Curtis R., Holt, William F., Young, Richard, Glennon, Richard A., Hellberg, Mark R., Dean, Thomas R

Journal:

Journal of Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 718 KB

english, 2015

29

Rapid Identification of Novel Inhibitors of the Human Aquaporin-1 Water Channel

Patil, Rajkumar V., Xu, Shouxi, van Hoek, Alfred N., Rusinko, Andrew, Feng, Zixia, May, Jesse, Hellberg, Mark, Sharif, Najam A., Wax, Martin B., Irigoyen, Macarena, Carr, Grant, Brittain, Tom, Brown,

Journal:

Chemical Biology & Drug Design

Year:

2016

Language:

english

File:

PDF, 1.70 MB

english, 2016

30

Agonists at the Serotonin Receptor (5-HT 1A ) Protect the Retina from Severe Photo-Oxidative Stress

Collier, Robert J., Patel, Yamini, Martin, Elizabeth A., Dembinska, Olga, Hellberg, Mark, Krueger, D. Scott, Kapin, Michael A., Romano, Carmelo

Journal:

Investigative Ophthalmology & Visual Science

Year:

2011

Language:

english

File:

PDF, 972 KB

english, 2011

31

Population expansion of an Antarctic king crab?

Hellberg, Michael E., Aronson, Richard B., Smith, Kathryn E., Duhon, Mark I., Ahyong, Shane T., Lovrich, Gustavo A., Thatje, Sven, McClintock, James B.

Journal:

Frontiers of Biogeography

Year:

2019

Language:

english

File:

PDF, 983 KB

english, 2019

32

Mating induces switch from hormone-dependent to hormone-independent steroid receptor–mediated growth in Drosophila secondary cells

Leiblich, Aaron, Hellberg, Josephine E. E. U., Sekar, Aashika, Gandy, Carina, Mendes, Claudia C., Redhai, Siamak, Mason, John, Wainwright, Mark, Marie, Pauline, Goberdhan, Deborah C. I., Hamdy, Freddi

Journal:

Year:

2019

Language:

english

File:

PDF, 32.21 MB

english, 2019

33

Population expansion of an Antarctic king crab?

Hellberg, Michael E., Aronson, Richard B., Smith, Kathryn E., Duhon, Mark I., Ahyong, Shane T., Lovrich, Gustavo A., Thatje, Sven, McClintock, James B.

Journal:

Frontiers of Biogeography

Year:

2019

File:

PDF, 983 KB

2019